Abstract Library

#2885 Ectopic Neuroendocrine Carcinoma: An Occult Source of ACTH

Introduction: About 250 cases of ectopic ACTH-producing neuroendocrine carcinoma (ACTH-NEC) have been reported; however metastatic ACTH-NEC of unknown primary is very rare. Usually are characterized by having a large cell, small cell, poorly differentiated or anaplastic cell, and Ki-67 index between 40-90%.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Huertas Gnecco B

Authors: Huertas Gnecco B, González Devia D, Alvaréz Figueroa J, Aguirre Matallana D, Cañón Solano D,

Keywords: Ectopic ACTH production, Cushing’s syndrome, Neuroendocrine carcinoma, Paraneoplastic Cushing syndrome, Ectopic Cushing´s syndrome,

#2233 Potential Effects of Ketoconazole on ACTH-Producing and Non-ACTH-Producing Neuroendocrine Tumors

Introduction: Prolonged biochemical remission after treatment with steroidogenesis inhibitors has been described in patients with Cushing’s syndrome due to ectopic adrenocorticotropin hormone (ACTH) production. Some studies have suggested antiproliferative and apoptotic effect of ketoconazole in human cancer cells.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Herrera-Martínez A

Authors: Herrera-Martínez A, Feelders R, Castaño J, Van Dungen R, Dogan-Oruc F,

Keywords: ACTH- and non-ACTH producing NETs, ketoconazole, somatostatin analogs, apoptosis, cytotoxicity,

#2064 The Difficulties in Managing Metastatic Pancreatic Neuroendocrine Tumours (pNETs) Causing Cushing’s Syndrome (CS)

Introduction: The pNETs causing CS are very rare and aggressive. Despite the use of various therapeutic modalities, their management is not well-established, representing nowadays a challenge.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Simó-Servat A, Teulé A, Sánchez C, Díez J, Iglesias P,

Keywords: pNETs, cushing syndrome,

#1453 Clinicopathologic Features, Treatments and Survival of Patients with Ectopic Cushing’s Syndrome from Neuroendocrine Tumors: Data from an Italian Multicenter Study

Introduction: Literature on ectopic Cushing syndrome (ECS) and NET is scarce

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Davì M

Authors: Davì M, Cosaro E, Piacentini S, Reimondo G, Albiger N,

Keywords: Ectopic ACTH,

#1143 Ectopic Cushing’s Syndrome (ECS) in Patients with Neuroendocrine Neoplasms

Introduction: Ectopic Cushing syndrome (ECS) has been described in patients with neuroendocrine neoplasms (NENs)

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Chatzellis E

Authors: Alexandraki K, Boutzios G, Papaoikonomou E, Chatzellis E, Chrysochoou M,

Keywords: ECS,